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Episode 1
In May 1893, Chicago's World's Fair is in full swing. A young woman arrives in the city to start a new job as an assistant to Dr. H.H. Holmes, but...
Episode 2
Dr. H.H. Holmes designed his entire hotel with murder in mind. Business is thriving - until Holmes is forced to choose between his latest mistress or his wife.
Episode 3
Serial killer Dr. H.H. Holmes racks up quite a body count. When detectives begin closing in, he invents new scams in order to found his finale escape from Chicago.